ACOT4 (acyl-CoA thioesterase 4)

2014-11-01  

Identity

HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
PTE-Ib,PTE1B,PTE2B
FUSION GENES

Other Information

Locus ID:

NCBI: 122970
MIM: 614314
HGNC: 19748
Ensembl: ENSG00000177465

Variants:

dbSNP: 122970
ClinVar: 122970
TCGA: ENSG00000177465
COSMIC: ACOT4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177465ENST00000326303Q8N9L9

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Biosynthesis of unsaturated fatty acidsKEGGko01040
Fatty acid elongationKEGGhsa00062
Biosynthesis of unsaturated fatty acidsKEGGhsa01040
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
161412032005The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes.22
259611512015Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.15

Citation

Dessen P

ACOT4 (acyl-CoA thioesterase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60091/acot4