ACOT7 (acyl-CoA thioesterase 7)

2003-05-01  

Identity

HGNC
LOCATION
1p36.31
LOCUSID
ALIAS
ACH1,ACT,BACH,CTE-II,LACH,LACH1,hBACH
FUSION GENES

Other Information

Locus ID:

NCBI: 11332
MIM: 602587
HGNC: 24157
Ensembl: ENSG00000097021

Variants:

dbSNP: 11332
ClinVar: 11332
TCGA: ENSG00000097021
COSMIC: ACOT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000097021ENST00000361521O00154
ENSG00000097021ENST00000377842O00154
ENSG00000097021ENST00000377845O00154
ENSG00000097021ENST00000377855O00154
ENSG00000097021ENST00000377860O00154
ENSG00000097021ENST00000418124O00154
ENSG00000097021ENST00000473466K7EKP8
ENSG00000097021ENST00000545482O00154
ENSG00000097021ENST00000608083O00154

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Biosynthesis of unsaturated fatty acidsKEGGko01040
Fatty acid elongationKEGGhsa00062
Biosynthesis of unsaturated fatty acidsKEGGhsa01040
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
155927552004Aberrant cytosolic acyl-CoA thioester hydrolase in hippocampus of patients with mesial temporal lobe epilepsy.9
197248952009Association of gene polymorphisms with chronic kidney disease in Japanese individuals.7
124353882002Human brain acyl-CoA hydrolase isoforms encoded by a single gene.5
285181462017Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway.5
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
284724012017WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.2
316400822019Expression level of ACOT7 influences the prognosis in acute myeloid leukemia patients.0

Citation

Dessen P

ACOT7 (acyl-CoA thioesterase 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/740/acot7