ATP6V1C1 (ATPase H+ transporting V1 subunit C1)

2007-02-01  

Identity

HGNC
LOCATION
8q22.3
LOCUSID
ALIAS
ATP6C,ATP6D,VATC,Vma5
FUSION GENES

Other Information

Locus ID:

NCBI: 528
MIM: 603097
HGNC: 856
Ensembl: ENSG00000155097

Variants:

dbSNP: 528
ClinVar: 528
TCGA: ENSG00000155097
COSMIC: ATP6V1C1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155097ENST00000395862P21283
ENSG00000155097ENST00000395862A0A024R9I0
ENSG00000155097ENST00000518738P21283
ENSG00000155097ENST00000518738A0A024R9I0
ENSG00000155097ENST00000518857E7EV59
ENSG00000155097ENST00000521514E7EV59

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
mTOR signaling pathwayKEGGko04150
Vibrio cholerae infectionKEGGko05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGko05120
Oxidative phosphorylationKEGGhsa00190
mTOR signaling pathwayKEGGhsa04150
Vibrio cholerae infectionKEGGhsa05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGhsa05120
Metabolic pathwaysKEGGhsa01100
Collecting duct acid secretionKEGGko04966
Collecting duct acid secretionKEGGhsa04966
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
Synaptic vesicle cycleKEGGko04721
Synaptic vesicle cycleKEGGhsa04721
V-type ATPase, eukaryotesKEGGhsa_M00160
V-type ATPase, eukaryotesKEGGM00160
ROS, RNS production in phagocytesREACTOMER-HSA-1222556
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by Insulin receptorREACTOMER-HSA-74752
Insulin receptor recyclingREACTOMER-HSA-77387
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Iron uptake and transportREACTOMER-HSA-917937
Transferrin endocytosis and recyclingREACTOMER-HSA-917977
Ion channel transportREACTOMER-HSA-983712

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208197782010MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.21
244547532014Atp6v1c1 may regulate filament actin arrangement in breast cancer cells.14
215269102012Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa.12
285049702017Osteoclast proton pump regulator Atp6v1c1 enhances breast cancer growth by activating the mTORC1 pathway and bone metastasis by increasing V-ATPase activity.10
307817502019MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H⁺ Transporting V1 Subunit C1.2
128905562003Structural and functional characterization of two human V-ATPase subunit gene promoters.1
259014222015The use of tissue microarrays for semiquantitative evaluation of ATPaseC1 expression is ineffective.1

Citation

Dessen P

ATP6V1C1 (ATPase H+ transporting V1 subunit C1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45846/atp6v1c1