CD180 (CD180 molecule)

2003-11-01  

Identity

HGNC
LOCATION
5q12.3
LOCUSID
ALIAS
LY64,Ly78,RP105
FUSION GENES

Other Information

Locus ID:

NCBI: 4064
MIM: 602226
HGNC: 6726
Ensembl: ENSG00000134061

Variants:

dbSNP: 4064
ClinVar: 4064
TCGA: ENSG00000134061
COSMIC: CD180

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134061ENST00000256447Q99467

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Toll-Like Receptors CascadesREACTOMER-HSA-168898
Toll Like Receptor 4 (TLR4) CascadeREACTOMER-HSA-166016

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
158520072005Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105.122
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.29
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
219592642011Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family.16
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
174485662007Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis.8
280052672017Human gingiva transcriptome during wound healing.6
202333312010In vivo expression of Toll-like receptor 2, Toll-like receptor 4, CSF2 and LY64 in Chinese chronic periodontitis patients.5

Citation

Dessen P

CD180 (CD180 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41219/cd180