CSNK1G2 (casein kinase 1 gamma 2)

2006-10-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
CK1g2
FUSION GENES

Other Information

Locus ID:

NCBI: 1455
MIM: 602214
HGNC: 2455
Ensembl: ENSG00000133275

Variants:

dbSNP: 1455
ClinVar: 1455
TCGA: ENSG00000133275
COSMIC: CSNK1G2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133275ENST00000255641P78368
ENSG00000133275ENST00000585957A0A087WW97
ENSG00000133275ENST00000585959A0A087WWF5
ENSG00000133275ENST00000589350K7EJC0
ENSG00000133275ENST00000589385K7ESB6
ENSG00000133275ENST00000591002A0A087WXD7
ENSG00000133275ENST00000591752K7EP38
ENSG00000133275ENST00000615564A0A087WZK4

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Hedgehog signaling pathwayKEGGko04340
Hedgehog signaling pathwayKEGGhsa04340
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Disassembly of the destruction complex and recruitment of AXIN to the membraneREACTOMER-HSA-4641262
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Sphingolipid de novo biosynthesisREACTOMER-HSA-1660661

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
159172222005SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.105
190052132009Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin.18
150771952004Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase.14
187948082008Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling.12
300268722018Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.5
153421222004Polymorphisms of casein kinase I gamma 2 gene associated with simple febrile seizures in Chinese Han population.3
288856132017MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia.1
153006312004[Five single nucleotide polymorphisms of casein kinase I gamma 2 gene in children with familial febrile convulsions].0
153006312004[Five single nucleotide polymorphisms of casein kinase I gamma 2 gene in children with familial febrile convulsions].0

Citation

Dessen P

CSNK1G2 (casein kinase 1 gamma 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43219/csnk1g2