CSPP1 (centrosome and spindle pole associated protein 1)

2015-02-01  

Identity

HGNC
LOCATION
8q13.1
LOCUSID
ALIAS
CSPP,CSPP-L,JBTS21
FUSION GENES

Other Information

Locus ID:

NCBI: 79848
MIM: 611654
HGNC: 26193
Ensembl: ENSG00000104218

Variants:

dbSNP: 79848
ClinVar: 79848
TCGA: ENSG00000104218
COSMIC: CSPP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104218ENST00000262210Q1MSJ5
ENSG00000104218ENST00000519163F2Z2M5
ENSG00000104218ENST00000519668Q1MSJ5
ENSG00000104218ENST00000519701E5RGA5
ENSG00000104218ENST00000521919E5RI67

Expression (GTEx)

0
5
10
15
20
25

References

Pubmed IDYearTitleCitations
243608082014Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy.48
243608032014Mutations in CSPP1, encoding a core centrosomal protein, cause a range of ciliopathy phenotypes in humans.30
243608072014Mutations in CSPP1 lead to classical Joubert syndrome.27
205194412010CSPP is a ciliary protein interacting with Nephrocystin 8 and required for cilia formation.26
191294812009Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle.24
155802902005Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization.21
168265652006CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization.13
168265652006CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization.13
263782392015Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis.9
309652362019circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.8

Citation

Dessen P

CSPP1 (centrosome and spindle pole associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55031/cspp1