CTSO (cathepsin O)

2017-01-01  

Identity

HGNC
LOCATION
4q32.1
LOCUSID
ALIAS
CTSO1
FUSION GENES

Other Information

Locus ID:

NCBI: 1519
MIM: 600550
HGNC: 2542
Ensembl: ENSG00000256043

Variants:

dbSNP: 1519
ClinVar: 1519
TCGA: ENSG00000256043
COSMIC: CTSO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000256043ENST00000433477P43234

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
ApoptosisKEGGko04210
ApoptosisKEGGhsa04210
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
289683982017SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.5
264823742016Prognostic impact of a single-nucleotide polymorphism near the CTSO gene in hormone receptor-positive breast cancer patients.3
230093862012Molecular insight into propeptide-protein interactions in cathepsins L and O.0

Citation

Dessen P

CTSO (cathepsin O)

Atlas Genet Cytogenet Oncol Haematol. 2017-01-01

Online version: http://atlasgeneticsoncology.org/gene/56691/ctso