DPP7 (dipeptidyl peptidase 7)

2011-02-01  

Identity

HGNC
DPP7
LOCATION
9q34.3
LOCUSID
29952
ALIAS
DPP2,DPPII,QPP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29952
MIM: 610537
HGNC: 14892
Ensembl: ENSG00000176978

Variants:

dbSNP: 29952
ClinVar: 29952
TCGA: ENSG00000176978
COSMIC: DPP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176978ENST00000371579Q9UHL4
ENSG00000176978ENST00000463619R4GMR2
ENSG00000176978ENST00000470766R4GMU5
ENSG00000176978ENST00000472306R4GMV4
ENSG00000176978ENST00000473532R4GN05
ENSG00000176978ENST00000497375R4GNE8

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
125291752003Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII.32
195568822009Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence.12
229526282012Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.8
205349822010Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.6
188237582009Dipeptidyl peptidase II is not a marker for progression in melanoma.1

Citation

Dessen P

DPP7 (dipeptidyl peptidase 7)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52089/dpp7