ELP2 (elongator acetyltransferase complex subunit 2)

2014-11-01  

Identity

HGNC
LOCATION
18q12.2
LOCUSID
ALIAS
MRT58,SHINC-2,STATIP1,StIP
FUSION GENES

Other Information

Locus ID:

NCBI: 55250
MIM: 616054
HGNC: 18248
Ensembl: ENSG00000134759

Variants:

dbSNP: 55250
ClinVar: 55250
TCGA: ENSG00000134759
COSMIC: ELP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134759ENST00000350494Q6IA86
ENSG00000134759ENST00000351393Q6IA86
ENSG00000134759ENST00000358232Q6IA86
ENSG00000134759ENST00000423854Q6IA86
ENSG00000134759ENST00000442325Q6IA86
ENSG00000134759ENST00000539560Q6IA86
ENSG00000134759ENST00000540766H0YFW0
ENSG00000134759ENST00000540799K7ER35
ENSG00000134759ENST00000542430F5GYE9
ENSG00000134759ENST00000542824Q6IA86
ENSG00000134759ENST00000543127F5GX79
ENSG00000134759ENST00000544267F5GWY6
ENSG00000134759ENST00000545632F5GWY6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
258475812015ELP2 is a novel gene implicated in neurodevelopmental disabilities.21
2206931720114-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells.14
254177212014Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia.1

Citation

Dessen P

ELP2 (elongator acetyltransferase complex subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62806/elp2