GDPD5 (glycerophosphodiester phosphodiesterase domain containing 5)

2013-05-01  

Identity

HGNC
GDPD5
LOCATION
11q13.4
LOCUSID
81544
ALIAS
GDE2,PP1665
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81544
MIM: 609632
HGNC: 28804
Ensembl: ENSG00000158555

Variants:

dbSNP: 81544
ClinVar: 81544
TCGA: ENSG00000158555
COSMIC: GDPD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158555ENST00000336898Q8WTR4
ENSG00000158555ENST00000443276Q8NDN3
ENSG00000158555ENST00000526177Q8WTR4
ENSG00000158555ENST00000527820Q8NDN3
ENSG00000158555ENST00000529721Q8WTR4
ENSG00000158555ENST00000532435E9PJU5
ENSG00000158555ENST00000533784Q8WTR4
ENSG00000158555ENST00000533805Q8WTR4
ENSG00000158555ENST00000534322H0YEF5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Glycerophospholipid catabolismREACTOMER-HSA-6814848

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
222790382012Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer.23
276930462016Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.12
296359042018GDPD5, a target of miR-195-5p, is associated with metastasis and chemoresistance in colorectal cancer.12
175786822008Cloning and characterization of a human GDPD domain-containing protein GDPD5.3
292032332018Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish.3

Citation

Dessen P

GDPD5 (glycerophosphodiester phosphodiesterase domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53254/gdpd5