GLG1 (golgi glycoprotein 1)

2007-02-01  

Identity

HGNC
GLG1
LOCATION
16q23.1
LOCUSID
2734
ALIAS
CFR-1,ESL-1,MG-160,MG160
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2734
MIM: 600753
HGNC: 4316
Ensembl: ENSG00000090863

Variants:

dbSNP: 2734
ClinVar: 2734
TCGA: ENSG00000090863
COSMIC: GLG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090863ENST00000205061Q92896
ENSG00000090863ENST00000422840Q92896
ENSG00000090863ENST00000447066Q92896
ENSG00000090863ENST00000562090H3BM42
ENSG00000090863ENST00000565260H3BRD8
ENSG00000090863ENST00000565474H3BQT1
ENSG00000090863ENST00000567951H3BQU9
ENSG00000090863ENST00000627032H3BM42

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
220213702011Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow.152
271590432016Polysialylation and lipopolysaccharide-induced shedding of E-selectin ligand-1 and neuropilin-2 by microglia and THP-1 macrophages.18
184639752009A pilot genome-wide association study of early-onset breast cancer.11
212838322011C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.11
198442552010Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.9
253017302014E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis.9
157979222005A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization.7
191485082009Expression of E-selectin ligand-1 (CFR/ESL-1) on hepatic stellate cells: implications for leukocyte extravasation and liver metastasis.5
126846702003Identification of MG-160, a FGF binding medial Golgi sialoglycoprotein, in brain tumors: an index of malignancy in astrocytomas.4
267927202016E-selectin ligand-1 (ESL-1) is a novel adiponectin binding protein on cell adhesion.2

Citation

Dessen P

GLG1 (golgi glycoprotein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45675/glg1