HMG20A (high mobility group 20A)

2007-04-01  

Identity

HGNC
HMG20A
LOCATION
15q24.3
LOCUSID
10363
ALIAS
HMGX1,HMGXB1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10363
MIM: 605534
HGNC: 5001
Ensembl: ENSG00000140382

Variants:

dbSNP: 10363
ClinVar: 10363
TCGA: ENSG00000140382
COSMIC: HMG20A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140382ENST00000336216Q9NP66
ENSG00000140382ENST00000381714Q9NP66
ENSG00000140382ENST00000558176H0YK55
ENSG00000140382ENST00000558651H0YMS9
ENSG00000140382ENST00000558845H0YKL0
ENSG00000140382ENST00000559035H0YMG2
ENSG00000140382ENST00000559099H0YNS8
ENSG00000140382ENST00000560498H0YM80
ENSG00000140382ENST00000560867H0YKM5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
226934552012Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.83
225705002012Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex.23
256398692015HMG20A is required for SNAI1-mediated epithelial to mesenchymal transition.13
205304872010The interaction with HMG20a/b proteins suggests a potential role for beta-dystrobrevin in neuronal differentiation.10
294495302018The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.9
237079522013The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.8
309195292019Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus.1

Citation

Dessen P

HMG20A (high mobility group 20A)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46777/hmg20a