IDI2 (isopentenyl-diphosphate delta isomerase 2)

2014-11-01  

Identity

HGNC
LOCATION
10p15.3
LOCUSID
ALIAS
IPPI2

Other Information

Locus ID:

NCBI: 91734
MIM: 615389
HGNC: 23487
Ensembl: ENSG00000148377

Variants:

dbSNP: 91734
ClinVar: 91734
TCGA: ENSG00000148377
COSMIC: IDI2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148377ENST00000277517Q9BXS1

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Terpenoid backbone biosynthesisKEGGko00900
Terpenoid backbone biosynthesisKEGGhsa00900
Metabolic pathwaysKEGGhsa01100
C5 isoprenoid biosynthesis, mevalonate pathwayKEGGhsa_M00095
C5 isoprenoid biosynthesis, mevalonate pathwayKEGGM00095
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Cholesterol biosynthesisREACTOMER-HSA-191273

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
209556882010Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis.7
172021342007IDI2, a second isopentenyl diphosphate isomerase in mammals.5
259507362015Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in Lewy bodies.3
146290382003Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication.2

Citation

Dessen P

IDI2 (isopentenyl-diphosphate delta isomerase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64498/idi2