IPO5 (importin 5)

2003-05-01 Affiliation

Identity

HGNC

IPO5

LOCATION

13q32.2

LOCUSID

3843

ALIAS

IMB3,KPNB3,Pse1,RANBP5,imp5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3843
MIM: 602008
HGNC: 6402
Ensembl: ENSG00000065150

Variants:

dbSNP: 3843
ClinVar: 3843
TCGA: ENSG00000065150
COSMIC: IPO5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000065150	ENST00000261574	O00410
ENSG00000065150	ENST00000357602	O00410
ENSG00000065150	ENST00000357602	A0A024RDY0
ENSG00000065150	ENST00000403772	H0Y3V4
ENSG00000065150	ENST00000421861	E7ESZ1
ENSG00000065150	ENST00000460070	E7EV12
ENSG00000065150	ENST00000463157	C9JQT6
ENSG00000065150	ENST00000469360	H0Y8C6
ENSG00000065150	ENST00000471898	C9JZD8
ENSG00000065150	ENST00000475420	E7ETV3
ENSG00000065150	ENST00000480611	E7EWK4
ENSG00000065150	ENST00000480641	C9JZ53
ENSG00000065150	ENST00000481455	E7EX05
ENSG00000065150	ENST00000481689	E7ETV8
ENSG00000065150	ENST00000485433	C9J875
ENSG00000065150	ENST00000489058	C9J583
ENSG00000065150	ENST00000490369	F8WF30
ENSG00000065150	ENST00000490680	O00410
ENSG00000065150	ENST00000490680	A0A024RDY0
ENSG00000065150	ENST00000493281	C9JXE0
ENSG00000065150	ENST00000496368	E7ETV8
ENSG00000065150	ENST00000497270	E7EQT5
ENSG00000065150	ENST00000631030	A0A0D9SG25
ENSG00000065150	ENST00000651721	O00410
ENSG00000065150	ENST00000651721	A0A024RDY0

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Disease	REACTOME	R-HSA-1643685
Infectious disease	REACTOME	R-HSA-5663205
Influenza Infection	REACTOME	R-HSA-168254
Influenza Life Cycle	REACTOME	R-HSA-168255
Influenza Viral RNA Transcription and Replication	REACTOME	R-HSA-168273
vRNP Assembly	REACTOME	R-HSA-192905

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
17005651	2006	Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.	70
15507604	2004	The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors.	41
18455505	2008	Karyopherin beta3: a new cellular target for the HPV-16 E5 oncoprotein.	18
21562121	2011	Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5.	17
12620808	2003	The L1 major capsid protein of human papillomavirus type 11 interacts with Kap beta2 and Kap beta3 nuclear import receptors.	15
24196961	2013	IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling.	15
27528606	2016	Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.	12
26488411	2015	Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population.	10
19581934	2009	Impaired p53 binding to importin: a novel mechanism of cytoplasmic sequestration identified in oxaliplatin-resistant cells.	8
27094387	2016	Ebola virus encodes a miR-155 analog to regulate importin-α5 expression.	8

Citation

Dessen P

IPO5 (importin 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41102/ipo5