LGALS3BP (galectin 3 binding protein)

2003-06-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
90K,BTBD17B,CyCAP,M2BP,MAC-2-BP,TANGO10B,gp90
FUSION GENES

Other Information

Locus ID:

NCBI: 3959
MIM: 600626
HGNC: 6564
Ensembl: ENSG00000108679

Variants:

dbSNP: 3959
ClinVar: 3959
TCGA: ENSG00000108679
COSMIC: LGALS3BP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108679ENST00000262776Q08380
ENSG00000108679ENST00000262776A0A0S2Z3Y1
ENSG00000108679ENST00000585407K7EKQ5
ENSG00000108679ENST00000586720K7ELA1
ENSG00000108679ENST00000587251K7EN99
ENSG00000108679ENST00000587310K7ER67
ENSG00000108679ENST00000587311K7EQT9
ENSG00000108679ENST00000588198K7ERZ6
ENSG00000108679ENST00000588205K7EM15
ENSG00000108679ENST00000588899K7EM15
ENSG00000108679ENST00000588990K7ER67
ENSG00000108679ENST00000589527K7EP36
ENSG00000108679ENST00000589775K7ESM3
ENSG00000108679ENST00000589906K7EJY8
ENSG00000108679ENST00000591274K7ES75
ENSG00000108679ENST00000591778K7EJD3

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
14758079200290K (Mac-2 BP) and galectins in tumor progression and metastasis.51
119806462002Expression of 90K (Mac-2 BP) correlates with distant metastasis and predicts survival in stage I non-small cell lung cancer patients.29
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
243029792013Sialoglycoproteins and N-glycans from secreted exosomes of ovarian carcinoma cells.27
234435592013LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.26
214747932011Development of glycoprotein capture-based label-free method for the high-throughput screening of differential glycoproteins in hepatocellular carcinoma.25
184507432008Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma.24
224962292012Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6.24
184903832008Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K.22
229702412012Mac-2 binding protein is a novel E-selectin ligand expressed by breast cancer cells.22

Citation

Dessen P

LGALS3BP (galectin 3 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41143/lgals3bp