MAPK8IP2 (mitogen-activated protein kinase 8 interacting protein 2)

2007-12-01  

Identity

HGNC
MAPK8IP2
LOCATION
22q13.33
LOCUSID
23542
ALIAS
IB-2,IB2,JIP2,PRKM8IPL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23542
MIM: 607755
HGNC: 6883
Ensembl: ENSG00000008735

Variants:

dbSNP: 23542
ClinVar: 23542
TCGA: ENSG00000008735
COSMIC: MAPK8IP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008735ENST00000329492Q13387

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
MAPK signaling pathwayKEGGhsa04010

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
122440472002Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase.30
210481392010Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2.26

Citation

Dessen P

MAPK8IP2 (mitogen-activated protein kinase 8 interacting protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49912/mapk8ip2