MARVELD3 (MARVEL domain containing 3)

2012-01-01 Affiliation

Identity

HGNC

MARVELD3

LOCATION

16q22.2

LOCUSID

91862

ALIAS

MARVD3,MRVLDC3

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 91862
MIM: 614094
HGNC: 30525
Ensembl: ENSG00000140832

Variants:

dbSNP: 91862
ClinVar: 91862
TCGA: ENSG00000140832
COSMIC: MARVELD3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000140832	ENST00000268485	Q96A59
ENSG00000140832	ENST00000299952	Q96A59
ENSG00000140832	ENST00000565261	Q96A59
ENSG00000140832	ENST00000567501	H3BQK1
ENSG00000140832	ENST00000567566	J3KSM2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Tight junction	KEGG	ko04530
Tight junction	KEGG	hsa04530

References

Pubmed ID	Year	Title	Citations
20164257	2010	Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.	104
20028514	2009	Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family.	56
24567356	2014	MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.	24
21763689	2011	Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells.	20

Citation

Dessen P

MARVELD3 (MARVEL domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52542/marveld3