METTL8 (methyltransferase 8, methylcytidine)

2014-11-01 Affiliation

Identity

HGNC

METTL8

LOCATION

2q31.1

LOCUSID

79828

ALIAS

TIP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79828
MIM: 609525
HGNC: 25856
Ensembl: ENSG00000123600

Variants:

dbSNP: 79828
ClinVar: 79828
TCGA: ENSG00000123600
COSMIC: METTL8

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000123600	ENST00000375258	E7ETE0
ENSG00000123600	ENST00000392599	B5ME25
ENSG00000123600	ENST00000392604	Q9H825
ENSG00000123600	ENST00000438609	H7C2P8
ENSG00000123600	ENST00000442541	C9J3F1
ENSG00000123600	ENST00000442778	C9JE69
ENSG00000123600	ENST00000447486	Q9H825
ENSG00000123600	ENST00000453846	C9J6U8
ENSG00000123600	ENST00000612742	B3KW44

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
28655767	2017	Three distinct 3-methylcytidine (m³C) methyltransferases modify tRNA and mRNA in mice and humans.	29

Citation

Dessen P

METTL8 (methyltransferase 8, methylcytidine)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68929/mettl8