MIF4GD (MIF4G domain containing)

2016-10-01  

Identity

HGNC
MIF4GD
LOCATION
17q25.1
LOCUSID
57409
ALIAS
AD023,MIFD,SLIP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57409
MIM: 612072
HGNC: 24030
Ensembl: ENSG00000125457

Variants:

dbSNP: 57409
ClinVar: 57409
TCGA: ENSG00000125457
COSMIC: MIF4GD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125457ENST00000245551A9UHW6
ENSG00000125457ENST00000245551A0A0S2Z5T5
ENSG00000125457ENST00000325102A9UHW6
ENSG00000125457ENST00000325102A0A0S2Z5K9
ENSG00000125457ENST00000577542A9UHW6
ENSG00000125457ENST00000577542A0A0S2Z5S7
ENSG00000125457ENST00000578305J3QLN4
ENSG00000125457ENST00000579119J3QLJ5
ENSG00000125457ENST00000579194J3KSU6
ENSG00000125457ENST00000579297A9UHW6
ENSG00000125457ENST00000579297A0A0S2Z5S7
ENSG00000125457ENST00000579612J3QKW3
ENSG00000125457ENST00000580571J3KSB8
ENSG00000125457ENST00000580717J3QRZ6
ENSG00000125457ENST00000581777J3QLD1
ENSG00000125457ENST00000618645A9UHW6
ENSG00000125457ENST00000618645A0A0S2Z5K9
ENSG00000125457ENST00000649805A0A3B3IU65

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
180251072008SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.31
232861972013Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.10
232861972013Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.10
225327002012INT6 interacts with MIF4GD/SLIP1 and is necessary for efficient histone mRNA translation.9
243363292015MIF4G domain containing protein regulates cell cycle and hepatic carcinogenesis by antagonizing CDK2-dependent p27 stability.8

Citation

Dessen P

MIF4GD (MIF4G domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56590/mif4gd