MNS1 (meiosis specific nuclear structural 1)

2014-11-01  

Identity

HGNC
MNS1
LOCATION
15q21.3
LOCUSID
55329
ALIAS
HTX9,SPATA40

Other Information

Locus ID:

NCBI: 55329
MIM: 610766
HGNC: 29636
Ensembl: ENSG00000138587

Variants:

dbSNP: 55329
ClinVar: 55329
TCGA: ENSG00000138587
COSMIC: MNS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138587ENST00000260453Q8NEH6

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
159429582005Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.17
80326791994cDNA cloning and functional characterization of a meiosis-specific protein (MNS1) with apparent nuclear association.10
301488302018Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility.5

Citation

Dessen P

MNS1 (meiosis specific nuclear structural 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70354/mns1