MNT (MAX network transcriptional repressor)

2003-02-01 Affiliation

Identity

HGNC

MNT

LOCATION

17p13.3

LOCUSID

4335

ALIAS

MAD6,MXD6,ROX,bHLHd3,lncRNA-HAL

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4335
MIM: 603039
HGNC: 7188
Ensembl: ENSG00000070444

Variants:

dbSNP: 4335
ClinVar: 4335
TCGA: ENSG00000070444
COSMIC: MNT

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000070444	ENST00000174618	Q99583
ENSG00000070444	ENST00000575394	V9GY02

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19086036	2009	Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.	26
24731854	2015	The activities of MYC, MNT and the MAX-interactome in lymphocyte proliferation and oncogenesis.	16
27018948	2016	DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation.	10
17419941	2007	Mnt takes control as key regulator of the myc/max/mxd network.	9
17577784	2007	Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia.	7
15258910	2004	Expression and DNA-binding activity of MYCN/Max and Mnt/Max during induced differentiation of human neuroblastoma cells.	6
23860446	2013	Chromatin dynamics at the hTERT promoter during transcriptional activation and repression by c-Myc and Mnt in Xenopus leavis oocytes.	3
18155722	2008	Elucidation of the structural determinants responsible for the specific formation of heterodimeric Mxd1/Max b-HLH-LZ and its binding to E-box sequences.	2
22964333	2012	Identification of Max binding protein as a novel binding protein of Nck1 and characterization of its role in inhibiting human liver cancer SK-HEP-1 cells.	1
18457265	2007	[Expression and mutation of myc antagonist genes Mad1, Mxi1 and Rox in leukemia cells].	0

Citation

Dessen P

MNT (MAX network transcriptional repressor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41412/mnt