MRPS18C (mitochondrial ribosomal protein S18C)

2014-11-01  

Identity

HGNC
LOCATION
4q21.23
LOCUSID
ALIAS
CGI-134,MRP-S18-1,MRP-S18-c,MRPS18-1,S18mt-c,mrps18-c
FUSION GENES

Other Information

Locus ID:

NCBI: 51023
MIM: 611983
HGNC: 16633
Ensembl: ENSG00000163319

Variants:

dbSNP: 51023
ClinVar: 51023
TCGA: ENSG00000163319
COSMIC: MRPS18C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163319ENST00000295491Q9Y3D5
ENSG00000163319ENST00000295491A0A024RDH9
ENSG00000163319ENST00000505719H0Y9W2
ENSG00000163319ENST00000507019D6RCM2
ENSG00000163319ENST00000507349D6RE70
ENSG00000163319ENST00000509970H0YAG5

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
285269482017An innovative strategy to clone positive modifier genes of defects caused by mtDNA mutations: MRPS18C as suppressor gene of m.3946G>A mutation in MT-ND1 gene.0

Citation

Dessen P

MRPS18C (mitochondrial ribosomal protein S18C)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70477/mrps18c