NKIRAS2 (NFKB inhibitor interacting Ras like 2)

2014-11-01  

Identity

HGNC
NKIRAS2
LOCATION
17q21.2
LOCUSID
28511
ALIAS
KBRAS2,kappaB-Ras2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 28511
MIM: 604497
HGNC: 17898
Ensembl: ENSG00000168256

Variants:

dbSNP: 28511
ClinVar: 28511
TCGA: ENSG00000168256
COSMIC: NKIRAS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168256ENST00000307641Q9NYR9
ENSG00000168256ENST00000307641A0A024R1Z4
ENSG00000168256ENST00000316082H7BXP1
ENSG00000168256ENST00000393880Q9NYR9
ENSG00000168256ENST00000393880A0A024R1Z4
ENSG00000168256ENST00000393881Q9NYR9
ENSG00000168256ENST00000393881A0A024R1Z4
ENSG00000168256ENST00000393885Q9NYR9
ENSG00000168256ENST00000393885A0A024R1Z4
ENSG00000168256ENST00000449471Q9NYR9
ENSG00000168256ENST00000462043A0A0A0MTA0
ENSG00000168256ENST00000479407Q9NYR9
ENSG00000168256ENST00000485789K7ELL8
ENSG00000168256ENST00000491638K7EKE9
ENSG00000168256ENST00000585955K7ER26
ENSG00000168256ENST00000587337K7ERG2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
249010502014miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas.23
184344482009Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.10
206391962010KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.8

Citation

Dessen P

NKIRAS2 (NFKB inhibitor interacting Ras like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70852/nkiras2