NLRP14 (NLR family pyrin domain containing 14)

2014-11-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
CLR11.2,GC-LRR,NALP14,NOD5,PAN8
FUSION GENES

Other Information

Locus ID:

NCBI: 338323
MIM: 609665
HGNC: 22939
Ensembl: ENSG00000158077

Variants:

dbSNP: 338323
ClinVar: 338323
TCGA: ENSG00000158077
COSMIC: NLRP14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158077ENST00000299481Q86W24

Expression (GTEx)

0
1
2

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
190748852008Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.25
204031352010The genetics of NOD-like receptors in Crohn's disease.21
254030122015Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization.9
169318012006Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure.0
284233392017Germ-Cell-Specific Inflammasome Component NLRP14 Negatively Regulates Cytosolic Nucleic Acid Sensing to Promote Fertilization.0

Citation

Dessen P

NLRP14 (NLR family pyrin domain containing 14)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70875/nlrp14