NPNT (nephronectin)

2008-10-01  

Identity

HGNC
LOCATION
4q24
LOCUSID
ALIAS
EGFL6L,POEM
FUSION GENES

Other Information

Locus ID:

NCBI: 255743
MIM: 610306
HGNC: 27405
Ensembl: ENSG00000168743

Variants:

dbSNP: 255743
ClinVar: 255743
TCGA: ENSG00000168743
COSMIC: NPNT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168743ENST00000305572Q6UXI9
ENSG00000168743ENST00000379987Q6UXI9
ENSG00000168743ENST00000427316Q6UXI9
ENSG00000168743ENST00000453617Q6UXI9
ENSG00000168743ENST00000503451D6RH31
ENSG00000168743ENST00000504304D6RE63
ENSG00000168743ENST00000504787H0Y8M1
ENSG00000168743ENST00000505917H0YA60
ENSG00000168743ENST00000506666Q6UXI9
ENSG00000168743ENST00000514622Q6UXI9
ENSG00000168743ENST00000514837H0YAK9

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200108352010Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.251
198445732009MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7.68
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8
221727262012Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis.0
236894822012Nephronectin expression in glomeruli of renal biopsy specimens from various kidney diseases: nephronectin is expressed in the mesangial matrix expansion of diabetic nephropathy.0
277822062016NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase.0
284765572017Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases.0
311306972019Role of Nephronectin in Pathophysiology of Silicosis.0

Citation

Dessen P

NPNT (nephronectin)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50401/npnt