NR2F2 (nuclear receptor subfamily 2 group F member 2)

2007-04-01  

Identity

HGNC
NR2F2
LOCATION
15q26.2
LOCUSID
7026
ALIAS
ARP-1,ARP1,CHTD4,COUPTF2,COUPTFB,COUPTFII,NF-E3,SRXX5,SVP40,TFCOUP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7026
MIM: 107773
HGNC: 7976
Ensembl: ENSG00000185551

Variants:

dbSNP: 7026
ClinVar: 7026
TCGA: ENSG00000185551
COSMIC: NR2F2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185551ENST00000394166P24468
ENSG00000185551ENST00000394166F1D8R0
ENSG00000185551ENST00000394171P24468
ENSG00000185551ENST00000421109P24468
ENSG00000185551ENST00000453270P24468
ENSG00000185551ENST00000559679H3BTC2

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of white adipocyte differentiationREACTOMER-HSA-381340

References

Pubmed IDYearTitleCitations
205856272010Web-based, participant-driven studies yield novel genetic associations for common traits.155
187986932008Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.86
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
211510972011A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation.85
232016802013COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.71
231360342013MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.62
188152872009Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate.61
247029542014Rare variants in NR2F2 cause congenital heart defects in humans.46
201473772010COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis.45
192105442009COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.40

Citation

Dessen P

NR2F2 (nuclear receptor subfamily 2 group F member 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47203/nr2f2