OR51E1 (olfactory receptor family 51 subfamily E member 1)

2007-02-01  

Identity

HGNC
OR51E1
LOCATION
11p15.4
LOCUSID
143503
ALIAS
D-GPCR,DGPCR,GPR136,GPR164,OR51E1P,OR52A3P,POGR,PSGR2

Other Information

Locus ID:

NCBI: 143503
MIM: 611267
HGNC: 15194
Ensembl: ENSG00000180785

Variants:

dbSNP: 143503
ClinVar: 143503
TCGA: ENSG00000180785
COSMIC: OR51E1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180785ENST00000396952Q8TCB6
ENSG00000180785ENST00000396952A0A126GVF8
ENSG00000180785ENST00000530215E9PKL6

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
162062862006PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer.26
281165192017Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor.23
164914802006The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.19
231849102013Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.18
239699812013Olfactory receptor 51E1 as a novel target for diagnosis in somatostatin receptor-negative lung carcinoids.18
127321972003Novel human G-protein-coupled receptors.17
273740832016The activation of OR51E1 causes growth suppression of human prostate cancer cells.15

Citation

Dessen P

OR51E1 (olfactory receptor family 51 subfamily E member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45731/or51e1