OSTN (osteocrin)

2014-11-01 Affiliation

Identity

HGNC

OSTN

LOCATION

3q28

LOCUSID

344901

ALIAS

MUSCLIN

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 344901
MIM: 610280
HGNC: 29961
Ensembl: ENSG00000188729

Variants:

dbSNP: 344901
ClinVar: 344901
TCGA: ENSG00000188729
COSMIC: OSTN

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000188729	ENST00000339051	P61366
ENSG00000188729	ENST00000445281	C9JER6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	20
17951249	2007	Osteocrin is a specific ligand of the natriuretic Peptide clearance receptor that modulates bone growth.	19
29967939	2018	Sex-specific genetic predictors of Alzheimer's disease biomarkers.	14
14523025	2003	Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype.	0
17950246	2007	Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor.	0
27830782	2016	Evolution of Osteocrin as an activity-regulated factor in the primate brain.	0
28185530	2017	Increased circulating levels of musclin in newly diagnosed type 2 diabetic patients.	0

Citation

Dessen P

OSTN (osteocrin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71571/ostn