OTUD4 (OTU deubiquitinase 4)

2015-09-01  

Identity

HGNC
LOCATION
4q31.21
LOCUSID
ALIAS
DUBA6,HIN1,HSHIN1
FUSION GENES

Other Information

Locus ID:

NCBI: 54726
MIM: 611744
HGNC: 24949
Ensembl: ENSG00000164164

Variants:

dbSNP: 54726
ClinVar: 54726
TCGA: ENSG00000164164
COSMIC: OTUD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164164ENST00000447906Q01804
ENSG00000164164ENST00000454497Q01804
ENSG00000164164ENST00000504501D6RA27
ENSG00000164164ENST00000509620Q01804
ENSG00000164164ENST00000514973D6RI06

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
236565882013Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination.72
259441112015Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.26
293950662018OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signaling.11
265884852015Evolutionary Loss of Activity in De-Ubiquitylating Enzymes of the OTU Family.3

Citation

Dessen P

OTUD4 (OTU deubiquitinase 4)

Atlas Genet Cytogenet Oncol Haematol. 2015-09-01

Online version: http://atlasgeneticsoncology.org/gene/55390/otud4