PCDH8 (protocadherin 8)

2008-10-01  

Identity

HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
ARCADLIN,PAPC

Other Information

Locus ID:

NCBI: 5100
MIM: 603580
HGNC: 8660
Ensembl: ENSG00000136099

Variants:

dbSNP: 5100
ClinVar: 5100
TCGA: ENSG00000136099
COSMIC: PCDH8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136099ENST00000338862O95206
ENSG00000136099ENST00000338862A0A024QZ94
ENSG00000136099ENST00000377942O95206

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
184087672008PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer.56
222738482012Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma.16
229413312012Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer.14
259275892014Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer.14
128849752002Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.12
254864972014Promoter methylation of protocadherin8 is an independent prognostic factor for biochemical recurrence of early-stage prostate cancer.10
254164272014Aberrant methylation of PCDH8 is a potential prognostic biomarker for patients with clear cell renal cell carcinoma.6
293252302018Protocadherin-8 promotes invasion and metastasis via laminin subunit γ2 in gastric cancer.5
290260662017Aberrant Promoter Methylation of Protocadherin8 (PCDH8) in Serum is a Potential Prognostic Marker for Low Gleason Score Prostate Cancer.4
293245322018Low Expression of Protocadherin-8 Promotes the Progression of Ovarian Cancer.2

Citation

Dessen P

PCDH8 (protocadherin 8)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50452/pcdh8