PCYOX1 (prenylcysteine oxidase 1)

2014-11-01  

Identity

HGNC
PCYOX1
LOCATION
2p13.3
LOCUSID
51449
ALIAS
PCL1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51449
MIM: 610995
HGNC: 20588
Ensembl: ENSG00000116005

Variants:

dbSNP: 51449
ClinVar: 51449
TCGA: ENSG00000116005
COSMIC: PCYOX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116005ENST00000264441F8W8W4
ENSG00000116005ENST00000414812C9K055
ENSG00000116005ENST00000422380C9JGT6
ENSG00000116005ENST00000433351Q9UHG3
ENSG00000116005ENST00000451279C9JM55

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Terpenoid backbone biosynthesisKEGGko00900
Terpenoid backbone biosynthesisKEGGhsa00900

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
192532762009Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme.13
121868802002Stereospecificity and kinetic mechanism of human prenylcysteine lyase, an unusual thioether oxidase.3
289305872018Prenylcysteine oxidase 1, a pro-oxidant enzyme of low density lipoproteins.1

Citation

Dessen P

PCYOX1 (prenylcysteine oxidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71777/pcyox1