POLR1G (RNA polymerase I subunit G)

2008-05-01  

Identity

HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
ASE-1,ASE1,CAST,CD3EAP,PAF49,RPA34
FUSION GENES

Other Information

Locus ID:

NCBI: 10849
MIM: 107325
HGNC: 24219
Ensembl: ENSG00000117877

Variants:

dbSNP: 10849
ClinVar: 10849
TCGA: ENSG00000117877
COSMIC: POLR1G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117877ENST00000309424O15446
ENSG00000117877ENST00000589804O15446
ENSG00000117877ENST00000590794K7EMH2
ENSG00000117877ENST00000592852K7EQC8

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Promoter ClearanceREACTOMER-HSA-73854
RNA Polymerase I Transcription InitiationREACTOMER-HSA-73762
RNA Polymerase I Promoter EscapeREACTOMER-HSA-73772
RNA Polymerase I Chain ElongationREACTOMER-HSA-73777
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413
Positive epigenetic regulation of rRNA expressionREACTOMER-HSA-5250913
B-WICH complex positively regulates rRNA expressionREACTOMER-HSA-5250924

References

Pubmed IDYearTitleCitations
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
168179482006Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study.14
168179482006Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study.14
94262811997ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes.12
159365902005Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50.12
168097782006RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor.12
182893672008A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study.12
182893672008A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study.12
171313452007Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.10
166902072007Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study.6

Citation

Dessen P

POLR1G (RNA polymerase I subunit G)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50105/polr1g