POLR1H (RNA polymerase I subunit H)

2007-02-01  

Identity

HGNC
LOCATION
6p22.1
LOCUSID
ALIAS
A12.2,HTEX-6,HTEX6,Rpa12,TCTEX6,TEX6,ZNRD1,ZR14,hZR14,tctex-6

Other Information

Locus ID:

NCBI: 30834
MIM: 607525
HGNC: 13182
Ensembl: ENSG00000066379

Variants:

dbSNP: 30834
ClinVar: 30834
TCGA: ENSG00000066379
COSMIC: POLR1H

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000066379ENST00000332435Q9P1U0
ENSG00000066379ENST00000332435Q2L6J2
ENSG00000066379ENST00000359374Q9P1U0
ENSG00000066379ENST00000359374Q2L6J2
ENSG00000066379ENST00000376782Q9P1U0
ENSG00000066379ENST00000376782Q2L6J2
ENSG00000066379ENST00000376785Q9P1U0
ENSG00000066379ENST00000376785Q2L6J2

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
RNA polymeraseKEGGko03020
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
RNA polymeraseKEGGhsa03020
Metabolic pathwaysKEGGhsa01100
RNA polymerase I, eukaryotesKEGGhsa_M00182
RNA polymerase I, eukaryotesKEGGM00182
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Promoter ClearanceREACTOMER-HSA-73854
RNA Polymerase I Transcription InitiationREACTOMER-HSA-73762
RNA Polymerase I Promoter EscapeREACTOMER-HSA-73772
RNA Polymerase I Chain ElongationREACTOMER-HSA-73777
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413
Positive epigenetic regulation of rRNA expressionREACTOMER-HSA-5250913
B-WICH complex positively regulates rRNA expressionREACTOMER-HSA-5250924

References

Pubmed IDYearTitleCitations
191159492009Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).119
238932412014miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1.62
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
190503822009Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection.44
189820672008HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles.40
189820672008HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles.40
201927302010ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression.24
201927302010ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression.24
251108352015Expression quantitative trait loci in long non-coding RNA ZNRD1-AS1 influence both HBV infection and hepatocellular carcinoma development.19
196930882009The HLA-B/-C haplotype block contains major determinants for host control of HIV.12

Citation

Dessen P

POLR1H (RNA polymerase I subunit H)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43588/polr1h