POLR2M (RNA polymerase II subunit M)

2014-11-01  

Identity

HGNC
LOCATION
15q21.3
LOCUSID
ALIAS
GCOM1,GRINL1A,Gdown,Gdown1
FUSION GENES

Other Information

Locus ID:

NCBI: 81488
MIM: 606485
HGNC: 14862
Ensembl: ENSG00000255529

Variants:

dbSNP: 81488
ClinVar: 81488
TCGA: ENSG00000255529
COSMIC: POLR2M

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255529ENST00000299638P0CAP2
ENSG00000255529ENST00000380557P0CAP2
ENSG00000255529ENST00000464277E9PP13
ENSG00000255529ENST00000482852P0CAP2
ENSG00000255529ENST00000494490E9PP13
ENSG00000255529ENST00000649091Q6EEV4
ENSG00000255529ENST00000649091L0R6H6

Expression (GTEx)

0
5
10
15
20
25
30
35

References

Pubmed IDYearTitleCitations
222443312012Functional association of Gdown1 with RNA polymerase II poised on human genes.71
222443322012Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II.36
246342142014Regulation of RNA polymerase II termination by phosphorylation of Gdown1.10
204122992010Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A.5
245960852014Functional interactions of the RNA polymerase II-interacting proteins Gdown1 and TFIIF.4
277168202016Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation.1

Citation

Dessen P

POLR2M (RNA polymerase II subunit M)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72054/polr2m