POLR3K (RNA polymerase III subunit K)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C11,C11-RNP3,HLD21,My010,RPC10,RPC11,RPC12.5
FUSION GENES

Other Information

Locus ID:

NCBI: 51728
MIM: 606007
HGNC: 14121
Ensembl: ENSG00000161980

Variants:

dbSNP: 51728
ClinVar: 51728
TCGA: ENSG00000161980
COSMIC: POLR3K

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161980ENST00000293860Q9Y2Y1

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
RNA polymeraseKEGGko03020
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
RNA polymeraseKEGGhsa03020
Cytosolic DNA-sensing pathwayKEGGko04623
Cytosolic DNA-sensing pathwayKEGGhsa04623
Metabolic pathwaysKEGGhsa01100
RNA polymerase III, eukaryotesKEGGhsa_M00181
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
RNA polymerase III, eukaryotesKEGGM00181
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cytosolic sensors of pathogen-associated DNAREACTOMER-HSA-1834949
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase III TranscriptionREACTOMER-HSA-74158
RNA Polymerase III Abortive And Retractive InitiationREACTOMER-HSA-749476
RNA Polymerase III Transcription InitiationREACTOMER-HSA-76046
RNA Polymerase III Transcription Initiation From Type 1 PromoterREACTOMER-HSA-76061
RNA Polymerase III Transcription Initiation From Type 2 PromoterREACTOMER-HSA-76066
RNA Polymerase III Transcription Initiation From Type 3 PromoterREACTOMER-HSA-76071
RNA Polymerase III Chain ElongationREACTOMER-HSA-73780
RNA Polymerase III Transcription TerminationREACTOMER-HSA-73980

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
174990432007Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases.64
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.17

Citation

Dessen P

POLR3K (RNA polymerase III subunit K)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72062/polr3k