PPFIA4 (PTPRF interacting protein alpha 4)

2007-04-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 8497
MIM: 603145
HGNC: 9248
Ensembl: ENSG00000143847

Variants:

dbSNP: 8497
ClinVar: 8497
TCGA: ENSG00000143847
COSMIC: PPFIA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143847ENST00000272198O75335
ENSG00000143847ENST00000295706O75335
ENSG00000143847ENST00000367240B1APN9
ENSG00000143847ENST00000447715O75335
ENSG00000143847ENST00000599514M0R219
ENSG00000143847ENST00000599966O75335
ENSG00000143847ENST00000600426M0QZB5

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Release CycleREACTOMER-HSA-112310
Norepinephrine Neurotransmitter Release CycleREACTOMER-HSA-181430
Serotonin Neurotransmitter Release CycleREACTOMER-HSA-181429
Glutamate Neurotransmitter Release CycleREACTOMER-HSA-210500
Dopamine Neurotransmitter Release CycleREACTOMER-HSA-212676
Acetylcholine Neurotransmitter Release CycleREACTOMER-HSA-264642

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195361752009Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.30
284600222017Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci.15
205999432010Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell-cell contacts.5
291874402017Liprin-α4 as a Possible New Therapeutic Target for Pancreatic Cancer.1
218296492011Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity.0
308421472019Liprin-α4 as a New Therapeutic Target for SCLC as an Upstream Mediator of HIF1α.0

Citation

Dessen P

PPFIA4 (PTPRF interacting protein alpha 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46762/ppfia4