PWWP2A (PWWP domain containing 2A)

2014-11-01  

Identity

HGNC
PWWP2A
LOCATION
5q33.3
LOCUSID
114825
ALIAS
MST101
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114825
MIM: 617823
HGNC: 29406
Ensembl: ENSG00000170234

Variants:

dbSNP: 114825
ClinVar: 114825
TCGA: ENSG00000170234
COSMIC: PWWP2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170234ENST00000307063Q96N64
ENSG00000170234ENST00000456329Q96N64
ENSG00000170234ENST00000520662H0YC08
ENSG00000170234ENST00000521424H0YC06
ENSG00000170234ENST00000523662Q96N64
ENSG00000170234ENST00000524050H0YB44

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
286459172017Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.11
302282602018A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.8
303274632018PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.6
313769352019Dysregulation of cPWWP2A-miR-579 axis mediates dexamethasone-induced cytotoxicity in human osteoblasts.2

Citation

Dessen P

PWWP2A (PWWP domain containing 2A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/55062/pwwp2a