RAMAC (RNA guanine-7 methyltransferase activating subunit)

2018-11-01  

Identity

HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
C15orf18,FAM103A1,HsT19360,RAM,RAMMET

Other Information

Locus ID:

NCBI: 83640
MIM: 614547
HGNC: 31022
Ensembl: ENSG00000169612

Variants:

dbSNP: 83640
ClinVar: 83640
TCGA: ENSG00000169612
COSMIC: RAMAC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169612ENST00000304191Q9BTL3

References

Pubmed IDYearTitleCitations
220993062011RAM/Fam103a1 is required for mRNA cap methylation.25
242004672014RAM function is dependent on Kapβ2-mediated nuclear entry.9
313299322019Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations.2
279346332017c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production.1

Citation

Dessen P

RAMAC (RNA guanine-7 methyltransferase activating subunit)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80549/ramac