RAPGEF5 (Rap guanine nucleotide exchange factor 5)

2006-10-01  

Identity

HGNC
LOCATION
7p15.3
LOCUSID
ALIAS
GFR,MR-GEF,REPAC
FUSION GENES

Other Information

Locus ID:

NCBI: 9771
MIM: 609527
HGNC: 16862
Ensembl: ENSG00000136237

Variants:

dbSNP: 9771
ClinVar: 9771
TCGA: ENSG00000136237
COSMIC: RAPGEF5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136237ENST00000344041A8MQ07
ENSG00000136237ENST00000401957Q92565
ENSG00000136237ENST00000401957A0A0S2Z561
ENSG00000136237ENST00000405243E9PGY3
ENSG00000136237ENST00000420196C9JHM4
ENSG00000136237ENST00000451559F8WD32
ENSG00000136237ENST00000458533C9JBS6
ENSG00000136237ENST00000620335Q92565
ENSG00000136237ENST00000620335A0A0S2Z5S1
ENSG00000136237ENST00000665637A0A590UJR0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447321Depressive Disorder, MajorDiseaseClinicalAnnotationassociatedPD
PA452229antidepressantsChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62

Citation

Dessen P

RAPGEF5 (Rap guanine nucleotide exchange factor 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43446/rapgef5