ROPN1 (rhophilin associated tail protein 1)

2007-12-01  

Identity

HGNC
LOCATION
3q21.1
LOCUSID
ALIAS
CT91,ODF6,RHPNAP1,ROPN1A,ropporin
FUSION GENES

Other Information

Locus ID:

NCBI: 54763
MIM: 611757
HGNC: 17692
Ensembl: ENSG00000065371

Variants:

dbSNP: 54763
ClinVar: 54763
TCGA: ENSG00000065371
COSMIC: ROPN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000065371ENST00000184183Q9HAT0
ENSG00000065371ENST00000184183A0A140VKB2
ENSG00000065371ENST00000405845Q9HAT0
ENSG00000065371ENST00000405845A0A140VKB2
ENSG00000065371ENST00000459660Q9HAT0
ENSG00000065371ENST00000460743C9JP07
ENSG00000065371ENST00000467907C9J6H4
ENSG00000065371ENST00000479867Q9HAT0
ENSG00000065371ENST00000484329Q9HAT0
ENSG00000065371ENST00000495093Q9HAT0
ENSG00000065371ENST00000496145C9J012
ENSG00000065371ENST00000620893Q9HAT0
ENSG00000065371ENST00000620893A0A140VKB2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate Rhotekin and RhophilinsREACTOMER-HSA-5666185

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201078402010Kalirin: a novel genetic risk factor for ischemic stroke.26
201078402010Kalirin: a novel genetic risk factor for ischemic stroke.26
216545222011Cancer testis antigen, ropporin, is a potential target for multiple myeloma immunotherapy.10
212402912011CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.9
175519202007A yeast two-hybrid system using Sp17 identified Ropporin as a novel cancer-testis antigen in hematologic malignancies.7
220211752012Loss of ASP but not ROPN1 reduces mammalian ciliary motility.7
207057942011Functional expression of ropporin in human testis and ejaculated spermatozoa.4
257049932015Ropporin gene expression in infertile asthenozoospermic men with varicocele before and after repair.3
292473442018Molecular study of human sperm RNA: Ropporin and CABYR in asthenozoospermia.1

Citation

Dessen P

ROPN1 (rhophilin associated tail protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49887/ropn1