RTN2 (reticulon 2)

2010-01-01  

Identity

HGNC
RTN2
LOCATION
19q13.32
LOCUSID
6253
ALIAS
NSP2,NSPL1,NSPLI,SPG12
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6253
MIM: 603183
HGNC: 10468
Ensembl: ENSG00000125744

Variants:

dbSNP: 6253
ClinVar: 6253
TCGA: ENSG00000125744
COSMIC: RTN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125744ENST00000245923O75298
ENSG00000125744ENST00000344680O75298
ENSG00000125744ENST00000430715O75298
ENSG00000125744ENST00000587597Q7RTN0
ENSG00000125744ENST00000590526K7EMR7
ENSG00000125744ENST00000591286Q96CG9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
222322112012Mutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12.54
180967002008Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.24
95306221998Molecular cloning of a novel mouse gene with predominant muscle and neural expression.9
197207952009Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4.3

Citation

Dessen P

RTN2 (reticulon 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51254/rtn2