SLC6A20 (solute carrier family 6 member 20)

2014-11-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
IMINO,SIT1,XT3,Xtrp3
FUSION GENES

Other Information

Locus ID:

NCBI: 54716
MIM: 605616
HGNC: 30927
Ensembl: ENSG00000163817

Variants:

dbSNP: 54716
ClinVar: 54716
TCGA: ENSG00000163817
COSMIC: SLC6A20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163817ENST00000353278Q9NP91
ENSG00000163817ENST00000358525Q9NP91
ENSG00000163817ENST00000413781C9JIN6
ENSG00000163817ENST00000456124B7ZLW4

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Amino acid transport across the plasma membraneREACTOMER-HSA-352230
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Na+/Cl- dependent neurotransmitter transportersREACTOMER-HSA-442660

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
255344292015Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors.40
196579692009Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20).3
35712701987Kinetics of the intestinal brush border proline (Imino) carrier.2
301609742018Intestinal IMINO transporter SIT1 is not expressed in human newborns.2
249580702014A genetic variant in SLC6A20 is associated with Type 2 diabetes in white-European and Chinese populations.1
260497832016Association Analysis of SLC6A20 Polymorphisms With Hirschsprung Disease.1

Citation

Dessen P

SLC6A20 (solute carrier family 6 member 20)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73476/slc6a20