SOX8 (SRY-box transcription factor 8)

2009-05-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 30812
MIM: 605923
HGNC: 11203
Ensembl: ENSG00000005513

Variants:

dbSNP: 30812
ClinVar: 30812
TCGA: ENSG00000005513
COSMIC: SOX8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000005513ENST00000293894P57073

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
185122302008Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody.27
290717172018SOX8 regulates cancer stem-like properties and cisplatin-induced EMT in tongue squamous cell carcinoma by acting on the Wnt/β-catenin pathway.19
237399152013MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.17
193696352009Differential expression of SOX2 and SOX17 in testicular germ cell tumors.11
246436252014Oncogenicity of the transcription factor SOX8 in hepatocellular carcinoma.10
293737572018Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.10
254007312014miRNA-124 down-regulates SOX8 expression and suppresses cell proliferation in non-small cell lung cancer.9
244493442014Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.6
308771712019Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice.4
311948752019The SOXE transcription factors-SOX8, SOX9 and SOX10-share a bi-partite transactivation mechanism.4

Citation

Dessen P

SOX8 (SRY-box transcription factor 8)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50907/sox8