TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B)

2007-02-01  

Identity

HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
MGC:9349,RAF1B,RAFI63,SL1,TAFI63
FUSION GENES

Other Information

Locus ID:

NCBI: 9014
MIM: 604904
HGNC: 11533
Ensembl: ENSG00000115750

Variants:

dbSNP: 9014
ClinVar: 9014
TCGA: ENSG00000115750
COSMIC: TAF1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115750ENST00000263663Q53T94
ENSG00000115750ENST00000416181F8WDU0
ENSG00000115750ENST00000434858F8WE32
ENSG00000115750ENST00000492648U3KQ75
ENSG00000115750ENST00000625239F8WDU0

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Promoter ClearanceREACTOMER-HSA-73854
RNA Polymerase I Transcription InitiationREACTOMER-HSA-73762
RNA Polymerase I Promoter EscapeREACTOMER-HSA-73772
RNA Polymerase I Chain ElongationREACTOMER-HSA-73777
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
SIRT1 negatively regulates rRNA ExpressionREACTOMER-HSA-427359
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413
Positive epigenetic regulation of rRNA expressionREACTOMER-HSA-5250913
B-WICH complex positively regulates rRNA expressionREACTOMER-HSA-5250924

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
195030632009Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.55
219211982011Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors.29
219211992011TAF1B is a TFIIB-like component of the basal transcription machinery for RNA polymerase I.25
265934432015AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription.15
121407582002Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability.11
260237732015Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis.11

Citation

Dessen P

TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46234/taf1b