TAF7L (TATA-box binding protein associated factor 7 like)

2013-08-01 Affiliation

Identity

HGNC

TAF7L

LOCATION

Xq22.1

LOCUSID

54457

ALIAS

CT40,TAF2Q

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54457
MIM: 300314
HGNC: 11548
Ensembl: ENSG00000102387

Variants:

dbSNP: 54457
ClinVar: 54457
TCGA: ENSG00000102387
COSMIC: TAF7L

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000102387	ENST00000324762	Q5H9L4
ENSG00000102387	ENST00000324762	A0A024RCI3
ENSG00000102387	ENST00000356784	Q5H9L4
ENSG00000102387	ENST00000372907	Q5H9L4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Basal transcription factors	KEGG	ko03022
Basal transcription factors	KEGG	hsa03022
Disease	REACTOME	R-HSA-1643685
Infectious disease	REACTOME	R-HSA-5663205
HIV Infection	REACTOME	R-HSA-162906
HIV Life Cycle	REACTOME	R-HSA-162587
Late Phase of HIV Life Cycle	REACTOME	R-HSA-162599
Transcription of the HIV genome	REACTOME	R-HSA-167172
HIV Transcription Initiation	REACTOME	R-HSA-167161
RNA Polymerase II HIV Promoter Escape	REACTOME	R-HSA-167162
Gene Expression	REACTOME	R-HSA-74160
Generic Transcription Pathway	REACTOME	R-HSA-212436
Transcriptional Regulation by TP53	REACTOME	R-HSA-3700989
RNA Polymerase II Transcription	REACTOME	R-HSA-73857
RNA Polymerase II Pre-transcription Events	REACTOME	R-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	REACTOME	R-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter Clearance	REACTOME	R-HSA-76042
RNA Polymerase II Transcription Initiation	REACTOME	R-HSA-75953
RNA Polymerase II Promoter Escape	REACTOME	R-HSA-73776
Regulation of TP53 Activity	REACTOME	R-HSA-5633007
Regulation of TP53 Activity through Phosphorylation	REACTOME	R-HSA-6804756

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
17714218	2007	Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure.	11
23292864	2013	Expression analysis of four testis-specific genes AURKC, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expression pattern.	10
16597641	2006	The role of the testis-specific gene hTAF7L in the aetiology of male infertility.	8
26107214	2015	Cancer/Testis OIP5 and TAF7L Genes are Up-Regulated in Breast Cancer.	6
25098277	2015	Frameshift mutations of TAF7L gene, a core component for transcription by RNA polymerase II, in colorectal cancers.	2
29307603	2018	An X-linked agammaglobulinemia contiguous gene syndrome with metachronous coprimary testicular cancers.	0

Citation

Dessen P

TAF7L (TATA-box binding protein associated factor 7 like)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53489/taf7l