TAS2R7 (taste 2 receptor member 7)

2014-11-01  

Identity

HGNC
TAS2R7
LOCATION
12p13.2
LOCUSID
50837
ALIAS
T2R7,TRB4

Other Information

Locus ID:

NCBI: 50837
MIM: 604793
HGNC: 14913
Ensembl: ENSG00000121377

Variants:

dbSNP: 50837
ClinVar: 50837
TCGA: ENSG00000121377
COSMIC: TAS2R7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121377ENST00000240687Q9NYW3

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
293554832018Plasticity of the ligand binding pocket in the bitter taste receptor T2R7.7
309281012019The human bitter taste receptor TAS2R7 facilitates the detection of bitter salts.3
317816302019Effect of Bitter Compounds on the Expression of Bitter Taste Receptor T2R7 Downstream Signaling Effectors in cT2R7/pDisplay-Gα16/gust44/pcDNA3.1 (+) Cells.0

Citation

Dessen P

TAS2R7 (taste 2 receptor member 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74505/tas2r7