TBKBP1 (TBK1 binding protein 1)

2014-11-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
ProSAPiP2,SINTBAD

Other Information

Locus ID:

NCBI: 9755
MIM: 608476
HGNC: 30140
Ensembl: ENSG00000198933

Variants:

dbSNP: 9755
ClinVar: 9755
TCGA: ENSG00000198933
COSMIC: TBKBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198933ENST00000361722A7MCY6
ENSG00000198933ENST00000537587F5H1U4
ENSG00000198933ENST00000578982J3KS71
ENSG00000198933ENST00000622396A7MCY6

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
RIG-I-like receptor signaling pathwayKEGGko04622
RIG-I-like receptor signaling pathwayKEGGhsa04622

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
175687782007SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK.67
308534022019The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria.31
236378482013Analysis of PPARGC1B, RUNX3 and TBKBP1 polymorphisms in Chinese Han patients with ankylosing spondylitis: a case-control study.7
254942922015Analysis of clinical indexes and RUNX3, TBKBP1, PPARGC1B polymorphisms in Chinese Han patients with ankylosing spondylitis.5
232863852013Identification of proteins that interact with TANK binding kinase 1 and testing for mutations associated with glaucoma.3
317923812019TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.1

Citation

Dessen P

TBKBP1 (TBK1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74544/tbkbp1