TENT2 (terminal nucleotidyltransferase 2)

2018-11-01  

Identity

HGNC
TENT2
LOCATION
5q14.1
LOCUSID
167153
ALIAS
APD4,GLD2,PAPD4,TUT2

Other Information

Locus ID:

NCBI: 167153
MIM: 614121
HGNC: 26776
Ensembl: ENSG00000164329

Variants:

dbSNP: 167153
ClinVar: 167153
TCGA: ENSG00000164329
COSMIC: TENT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164329ENST00000296783Q6PIY7
ENSG00000164329ENST00000423041Q6PIY7
ENSG00000164329ENST00000428308Q6PIY7
ENSG00000164329ENST00000453514Q6PIY7
ENSG00000164329ENST00000504233D6RAF2

References

Pubmed IDYearTitleCitations
230636542012Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.124
227276652012Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.56
232008562012Specific miRNA stabilization by Gld2-catalyzed monoadenylation.44
246673242014HBx down-regulated Gld2 plays a critical role in HBV-related dysregulation of miR-122.16
273669062016Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2.8
269261062016The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs.7
219956302011Involvement of hGLD-2 in cytoplasmic polyadenylation of human p53 mRNA.6
201449042010The early noncoding region of human papillomavirus type 16 is regulated by cytoplasmic polyadenylation factors.1
310570872019Gld2 activity is regulated by phosphorylation in the N-terminal domain.1

Citation

Dessen P

TENT2 (terminal nucleotidyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80489/tent2