TFAP2E (transcription factor AP-2 epsilon)

2012-01-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
AP-2epsilon,AP2E

Other Information

Locus ID:

NCBI: 339488
MIM: 614428
HGNC: 30774
Ensembl: ENSG00000116819

Variants:

dbSNP: 339488
ClinVar: 339488
TCGA: ENSG00000116819
COSMIC: TFAP2E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116819ENST00000373235Q6VUC0

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsREACTOMER-HSA-8864260
Activation of the TFAP2 (AP-2) family of transcription factorsREACTOMER-HSA-8866907
Negative regulation of activity of TFAP2 (AP-2) family transcription factorsREACTOMER-HSA-8866904

References

Pubmed IDYearTitleCitations
222168412012TFAP2E-DKK4 and chemoresistance in colorectal cancer.50
208623092010Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon.0
233316252013The transcription factor activating enhancer-binding protein epsilon (AP-2ε) regulates the core promoter of type II collagen (COL2A1).0
249969902014TFAP2E hypermethylation was associated with survival advantage in patients with colorectal cancer.0
258104912016Transcription Factor AP2ε: A Potential Predictor of Chemoresistance in Patients With Gastric Cancer.0
282601052017Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells.0
295351272018TFAP2E Methylation and Expression Status Does Not Predict Response to 5-FU-based Chemotherapy in Colorectal Cancer.0
311155332019TFAP2E methylation promotes 5‑fluorouracil resistance via exosomal miR‑106a‑5p and miR‑421 in gastric cancer MGC‑803 cells.0

Citation

Dessen P

TFAP2E (transcription factor AP-2 epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52562/tfap2e