TNR (tenascin R)

2003-05-01  

Identity

HGNC
LOCATION
1q25.1
LOCUSID
ALIAS
TN-R
FUSION GENES

Other Information

Locus ID:

NCBI: 7143
MIM: 601995
HGNC: 11953
Ensembl: ENSG00000116147

Variants:

dbSNP: 7143
ClinVar: 7143
TCGA: ENSG00000116147
COSMIC: TNR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116147ENST00000263525Q92752
ENSG00000116147ENST00000367674Q92752
ENSG00000116147ENST00000422274H0Y668

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
185210902009Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.44
206738682010A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).36
204524822010Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.26
175379732007Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R.19
265958082016Whole-Exome Sequencing in Familial Parkinson Disease.18
209507962011Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.15
232694782013Tenascins and inflammation in disorders of the nervous system.15
195734792009Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.12
146812222004Neuronal-specific synthesis and glycosylation of tenascin-R.9

Citation

Dessen P

TNR (tenascin R)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42649/tnr